Fetal Valproate Syndrome

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Fetal Valproate Syndrome is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Fetal Valproate Syndrome is a rare congenital disorder caused by exposure of the fetus to valproic acid (dalpro, depakene, depakote, depakote sprinkle, divalproex, epival, myproic acid) during the first three months of pregnancy. Valproic acid is an anticonvulsant drug used to control certain types of seizures in the treatment of epilepsy. A small percentage of pregnant women who take this medication can have a child with Fetal Valproate Syndrome. The exact prevalence of this condition remains to be established. Symptoms of this disorder may include spina bifida, distinctive facial features, and other musculoskeletal abnormalities.

Supporting Organizations

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
Website: http://rarediseases.info.nih.gov/GARD/

International Federation for Spina Bifida and Hydrocephalus

Cellebroersstraat 16
Brussels, B1000
Tel: 32025020413
Fax: 32025021129
Email: info@ifglobal.org
Website: http://www.ifglobal.org

Organisation For Anti-Convulsant Syndrome

23 Morriston Close
South Oxhey
Watford, WD196UB
United Kingdom
Tel: 4402083869271
Email: OACSsecretary@gmail.com
Website: http://www.oacscharity.org

Spina Bifida Association of America

4590 MacArthur Boulevard NW
Suite 250
Washington, DC 20007-4226
Tel: (202)944-3285
Fax: (202)944-3295
Tel: (800)621-3141
Email: sbaa@sbaa.org
Website: http://www.sbaa.org

Spina Bifida and Hydrocephalus Canada

Suite 647-167 av. Lombard Avenue
R3B 0V3
Tel: 2049253650
Fax: 2049253654
Tel: 8005659488
Email: info@sbhac.ca
Website: http://www.sbhac.ca

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  7/14/2015
Copyright  2003 National Organization for Rare Disorders, Inc.