Home > Health Library > Zollinger-Ellison Syndrome and Peptic Ulcer
Zollinger-Ellison syndrome is a rare condition in which tumors called
gastrinomas form in the pancreas or part of the upper small intestine
(duodenum). The tumors secrete large amounts of a hormone called gastrin.
Gastrin signals the stomach to produce more acid.
This syndrome is extremely rare, but it may be considered as a cause
when a person has severe or repeated peptic ulcers.
The main treatment for Zollinger-Ellison syndrome is taking proton pump inhibitors and removing the
tumors causing the overproduction of acid. If
this surgery is successful, you will no longer need to take medicines.
November 15, 2013
E. Gregory Thompson, MD - Internal Medicine & Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology
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