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Spasticity is a condition in which muscles are tight or stiff. For example, your hand may stay clenched in a fist or your knee may be hard to bend. At times the muscles may jerk or spasm uncontrollably. It can interfere with your ability to move, speak, or walk normally.
Spasticity usually occurs because of damage to the part of the brain or spinal cord that controls voluntary movement. It's often the result of a spinal cord injury, a stroke, or a disease such as multiple sclerosis, cerebral palsy, or amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).
Common symptoms include:
If spasticity isn't treated, the muscles may freeze in an abnormal position. This can be very painful.
The main treatments are physical therapy and medicines that help reduce muscle spasms. Surgery may be an option in severe cases.
Exercise and stretching are important treatments for spasticity. Therapists will work with you to increase your range of motion and keep your muscles from getting stiff. You will need to move the affected limb over and over again on a regular basis. You may do this on your own or with the help of a therapist, machine, or caregiver.
In some cases, cold packs and electrical stimulation are used on muscles. Casts or splints may be used to stretch the muscles and keep them from contracting.
Muscle relaxants (antispasmodics) are used to treat spasticity. They include baclofen (such as Gablofen) and tizanidine (Zanaflex). These medicines relax tight muscles and stop muscle spasms. But they may cause sleepiness, muscle weakness, and nausea.
Baclofen is the medicine most often prescribed for spasticity. You can take it as a pill, or a surgeon can implant a small pump under your skin that delivers the medicine directly to your spinal cord. The advantage of the pump is that you will use less medicine. This reduces the side effects that are a problem with baclofen pills. Your doctor can tell you if the pump is right for you.
Other medicines that may be used include gabapentin (such as Neurontin), diazepam (Valium), clonazepam (such as Klonopin), and dantrolene (Dantrium). In many cases, taking small doses of a combination of medicines works better and causes fewer side effects than taking a larger dose of a single medicine.
Botulinum toxin (such as Botox) injections given directly into the muscle can block messages that cause the muscle to spasm. The effect of one injection lasts about 3 to 4 months.
Some people try medical marijuana to relieve spasticity. But at present, experts don't recommend it because there is not enough evidence that its benefits are greater than its risks.
Some people with severe spasticity may need surgery. For example, surgery may be done to:
The National Institute of Neurological Disorders and
Stroke (NINDS), a part of the National Institutes of Health, is the leading
U.S. federal government agency supporting research on brain and nervous system
disorders. It provides the public with educational materials and information
about these disorders.
This not-for-profit organization provides support services and
information on holistic, alternative, and conventional medical care options for
people with multiple sclerosis (MS). It does not endorse any single health care
approach but provides information on all. It publishes a quarterly
This website offers educational materials and
information on services of the University of Alabama Spinal Cord Injury Model
System (UAB-SCIMS). It includes links to national organizations, government
agencies, commercial products, and educational resources related to spinal cord
Other Works Consulted
Keenan MAE, Mehta S (2006). Rehabilitation. In HB Skinner, ed., Current Diagnosis and Treatment in Orthopedics, 4th ed., pp. 671–727. New York: McGraw-Hill.
Leussink VI, et al. (2012). Symptomatic therapy in multiple sclerosis: The role of cannabinoids in treating spasticity. Therapeutic Advances in Neurological Disorders, 5(5): 255–266. Also available online: http://tan.sagepub.com/content/5/5/255.abstract.
Simpson DM, et al. (2008). Assessment: Botulinum neurotoxin for the treatment of spasticity (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology, 70(19): 1691–1698.
October 26, 2012
Anne C. Poinier, MD - Internal Medicine & Karin M. Lindholm, DO - Neurology
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