Home > Health Library > Prerenal Acute Renal Failure
acute renal failure (ARF) occurs when a sudden
reduction in blood flow to the kidney (renal hypoperfusion) causes a loss of
kidney function. In prerenal acute renal failure, there is nothing wrong with
the kidney itself.
Prerenal acute renal failure is the most common type of acute renal
failure, accounting for about 55 out of 100 acute renal failure cases.1 It can be a complication of almost any disease, condition, or
medicine that causes a decrease in the normal amount of blood and fluid in
Causes of prerenal acute renal failure include:
Treatment focuses on correcting the cause of the prerenal acute renal
failure. Depending on the cause, the condition often reverses itself within a
couple of days after normal blood flow to the kidneys has been restored.
But if it is not reversed or treated successfully and quickly, prerenal
acute renal failure can cause tissue death in the kidneys and lead to intrinsic
(intrarenal) acute renal failure.
Liu KD, Chertow GM (2008). Acute renal failure. In AS
Fauci et al., eds., Harrison's Principles of Internal Medicine, 17th ed., vol. 2, pp. 1752–1761. New York:
May 10, 2011
E. Gregory Thompson, MD - Internal Medicine & Tushar J. Vachharajani, MD, FASN, FACP - Nephrology
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